Thursday, August 29, 2013

Statins, what are the side effects?

In the previous blog, you can read all about cholesterol and its function in the body. The most important factor to take from the blog is that our cholesterol levels are produced by the liver, and they are only produced in response to a stimulus. For those who suffer from elevated cholesterol levels, especially elevated LDL levels, you really need to focus on your diet, because LDL's are the livers response to excess inflammation in the blood. If you use a statin drug to take away your LDLs, instead of focusing on the diet changes that are needed, you will have no organic response to fight the inflammation in the blood, and Diabetes is inevitable. 

Read this blog to dive farther into your knowledge of health, and learn how The New-Start Solution will get you back on the health track you desire.

As I stated before, all cholesterol is produced in the liver. Below is a diagram of how the sequence of events takes place for the production of cholesterol. 

As you can see, the big black line that has (STATINS) beside it is where statin drugs come in to inhibit the function of HMG-CoA reductase.

Blocking the function of HMG-CoA reductase inhibits the liver from continuing the step of turning HMG-CoA into Mevalonate.

 When this very important step along this pathway is stopped, you can see what fails to be produced, Ubiquinone, Cholesterol, and Dclichol.

I have spent a lot of time in the last blog talking about cholesterol and why its produced, but there is one other very important factor that I am going to discuss today. 

What is Ubiquinone????

You might have heard of a supplement out that is called CoQ10. Well that is the usable form of Ubiquinone in the body.

Would you be concerned if I told you that there is almost no way to produce adequate amounts of energy for our cells if you do not produce adequate Ubiquinone?


First, lets dive a little deeper into why the body needs Ubiquinone or CoQ10.

I often discuss how we need to properly fuel our body with the fuel that it needs to promote health and prevent illness. Well that fuel comes in three major forms, called Macronutrients. These macronutrients are based upon 3 groups, carbohydrates, proteins, and fats.

Each of these three macros have a basic function to fuel the body. Proteins are blocks of amino acids that are broken down and utilized throughout the body in basically ever function from muscle building, to RNA synthesis. Fats are different, they are utilized as the building blocks of cholesterol, and they help restore neurological function and provide lubrication for our joints in the body.

Carbohydrates are the most common macronutrient that you hear about. There are high carb diets, low carb diets, etc. But what are carbs exactly?

For the most part, carbohydrates are sugar. Sugar is the fuel for energy in the body. I am not going to go into the chemical compound of sugar or be technical about where the carbs we eat should come from. I am just going to discuss one derivative that comes from broken down carbohydrates.

I am in no way saying you should eat endless amounts of sugar because carbohydrates are the energy that our body needs. Vegetables are carbohydrates that we need to fuel the body not a Snickers Bar.

COFFEE, or CAFFEINE is not energy. No matter how much you think you cannot wake up or get through the day without coffee, you are wrong. Caffeine is a stimulant, that makes your body think it has energy and you are only further depriving your body of the energy that is demands.

So, lets talk about how carbohydrates become usable energy in the body.

Bear with me here, this is going to get a little boring, but I promise I will get back to the point of Ubiquinone eventually. 

Carbohydrates are sugar, and the most common usable form of sugar in the body is Glucose. I am sure you have heard of this compound. You might have even had a Glucose Tolerance Test before.

Glucose is the form of sugar that is readily usable in the body for energy. The real point of what I am about to say is this. Glucose, Sugar, Caffeine, Protein, Fat, and all other things we eat are not a usable form of energy in the human body. Adenosine Triphosphate (ATP) is the main thing that is really "energy" in the body. ATP is generated from Glucose, and here is how.

After we eat and digestion takes place to break down the carbs, proteins, and fats, the end result of our food either ends up in our blood stream or as poop.

When a carbohydrate is broken into glucose and your brain is telling your liver that you need some energy to be produced from this meal, the glucose enters the process called Glycolysis.

I am not going to bore you with the entire glycolysis process so here is a picture.

 As you can clearly see, the glucose enters the pathway and produces some energy for the body:
  • 2 ATP
  • 2 NADH+
  • 2 Pyruvate.
 This is just the start of the metabolic pathway, and to be completely honest, the two ATP produced doesn't mean too much. Our major energy producer is still to come.

So what happens next?

Well the two ATP can be used in the body wherever it need, the NADH+ are put on the back burner for future use, which you will find out shortly, and the two pyruvate compounds go on to enter the Krebs Cycle. (do you remember me talking about the Krebs Cycle in the fibromyalgia blog?)

Again, I won't bore you with the pathway of the Krebs Cycle, so here is a picture.

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 As you can clearly see, each of the two pyruvate gets into the Krebs Cycle and produces:
  • 2 ATP 
  • 2 FADH2 
  • 6 NADH+
Again, these ATP are free to be utilized anywhere in the body and all of the NADH+ and FADH2 are sent to the next and most important pathway for energy production or cell respiration. These compounds enter the Electron Transport Chain (ETC).

Here in the ETC is where the vast majority of you energy is produced. Out of the 30-32 ATP that is produced from each glucose molecule, 24-26 are produced by the ETC.

You are probably started to wonder, why in the world is Dr. Moz still talking about ATP and glucose and endless metabolic pathways. Well here is the kicker, Statin drugs are dangerous because they stop the production of Ubiquinone. Ubiquinone is utilized in the body as CoQ10 and CoQ10 is a vital instrument in the ETC. Considering the ETC produces 80% of our cells' usable energy, I think it is important to discuss it.

Here is the ETC pathway.

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As you can see in this diagram, all of the NADH+ and FADH2 are being utilized through an oxidation/reduction reaction (requires vitamins B2 & B3) to produce ATP across the membrane of the mitochondria. And when each of these molecules are broken down, Ubiquinone, or CoQ10 is utilized to transport the hydrogen ion across the membrane.

So what happens with you do block the body from producing Ubiquinone with a common Statin Medication? You stop the production of ATP. You inhibit your body from carrying out its daily routine.

Are There Side Effects of Statin Drugs?

Most people who take statin drugs tolerate them very well. But some people experience side effects.
The most common statin side effects include:
  • Headache
  • Difficulty sleeping
  • Flushing of the skin
  • Muscle aches, tenderness, or weakness (myalgia)
  • Drowsiness
  • Dizziness
  • Nausea and/or vomiting
  • Abdominal cramping and/or pain
  • Bloating and/or gas
  • Diarrhea
  • Constipation
  • Rash
All of these side effects have to do with poor cell activity and decreased overall energy levels. Think about this when your doctor tries to prescribe you a statin medication.

Dr. Moz

If you are tired of seeking pain relief with no results, call (812) 799-0668 TODAY and schedule a FREE CONSULTATION, and let's get you back to the PAIN-FREE Life you are missing.

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Tuesday, August 13, 2013

Cholesterol, Statins, The Hidden Truth

If you have been following my blogs, I think you know and understand my compassion about the adverse effects of using antacid medications. I have discussed how they are actually a poison and can cause disease.

I am going to switch gears for a few weeks discussing a new topic. CHOLESTEROL. So strange, even when I read that word, I associate it with bad health, and heart disease.

Do You?

If you say yes, then you are another victim of skewed science and great marketing by the pharmaceutical industry. Get ready for a series of blogs that will help you understand the truth behind cholesterol, and learn about another health crippling medication that millions of Americans are already taking.

Nearly every person has been exposed to the random blood screen for “wellness” where they check your blood for possible problems. They always analyze your total cholesterol levels and then try to explain to you how bad your need to get the total level lower. They seldom analyze the ratio of HDL:LDL and they seldom explain to you why your cholesterol levels are high. The only purpose of this screen is to scare you into thinking that your cholesterol levels will lead to possible heart disease and the only way to keep this from happening is to figure out the proper dose of a Statin (a cholesterol lowering medication) that your body needs to keep this excess in cholesterol at bay. But is there any clinical study to back up that scare tactic?

The answer is NO.
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The small print, no drug company wants to publish.

THERE HAS BEEN ZERO CLINICAL STUDIES THAT SHOW TAKING A STATIN MEDICATION WILL LOWER YOUR CHANCE OF HEART DISEASE. On the bright side, there has been some small evidence that if males have had a heart attack, taking a statin drug will reduce his risk of having a second heart attack. Do you know what I think is a more logical factor of what prevents males from having a second heart attack? Maybe its because they had a first heart attack, and then had to realize that they need to make some changes in their life, because a heart attack is pretty serious.

Here is what a Statin Drug does to inhibit production of cholesterol. 

As you can see, statin drugs inhibit the function of HMG-CoA Reductase to convert HMG-CoA to Mevalonate.

Did you just read that, I said "Inhibits the function of something...

Lets go back to the definition of poison, shall we?

poison [ˈpɔɪzən]
1. (Medicine) any substance that can impair function, cause structural damage, or otherwise injure the body

Do the statin medications fall under the classification as a poison????

I hope you are wondering, why is cholesterol demonized as the culprit behind heart disease and heart attacks???

Many years ago, autopsies were performed on a numerous amount of patients that met their maker in the hands of a heart attack. The blood analysis of these patients did show a high cholesterol level. This correlation is what spawned the idea of creating a medication that would decrease cholesterol levels. This concept does seem to make sense, but, I assume or hope, it was not fully understood why cholesterol is in the blood stream.

If you think that having high cholesterol levels is linked to eating a high fat diet, you are wrong. If you are worried about eating the yolk of an egg because of your cholesterol, sorry, that is ridiculous. Only 25% of the cholesterol that courses through your blood is a result of you eating fat. 75% of your total cholesterol levels in the blood are PRODUCED BY THE LIVER.

What is cholesterol?

Sorry, cholesterol is not just that fatty deposit that you find in your arteries when you have blockage.

Cholesterol is a HORMONE.

All hormones in the body are produced by the body, used by the body, and are absolutely necessary for health.

And CHOLESTEROL IS THE PRECURSOR TO almost EVERY MAJOR HORMONE!! Look at the chart to the right, progesterone, estrogen, and testosterone are formed from the break down of cholesterol.

Want to know some other functions that cholesterol has?
  • Fat metabolism
    • Yes, fat metabolism, eating saturated fats does not make you gain fat.
  • Cell development
  • Cell wall formation
  • Blood vessel wall strengthening
    • Yes, strengthening.
  • Bile production
    • This is how Cheerios lowers cholesterol. It requires bile to digest the fiber.
  • Vitamin D production
  • Nerve cell production
    • Statins have showed links to increasing prevalance of Alzheimer's
  • Production of lubrication fluids

I hope it is easy to understand why the liver produces cholesterol to support the health and life us each and every one of us, but I still need to answer the question.

Why, did all of the people that met their maker due to heart disease have high cholesterol levels???

Along with being a building block to many of the body's necessary hormones and being a major component in many of the body's natural function, cholesterol as one very important job to do, that without it, disease is inevitable.

Cholesterol is a natural anti inflammatory healing substance. It is required to decrease inflammation in the blood and other tissues. Without cholesterol, we absolutely cannot heal injured tissue.

If you have ever looked into your blood test or your cholesterol screening test, you will see a bunch of different levels that no one takes into consideration. HDL, LDL, VLDL, Triglycerides, ect. All of these have different meanings, but the big two that I am concerned with are HDL, and LDLs.

They always check your total cholesterol and if it is above 200, you are in trouble, Right?

Well what they never address is why that level is high. What causes your LDLs, or HDLs to be elevated in the blood stream. Well just so you know, the cause is often the solution. No statin drug will help with you real problem.

I will try to draw you a mental picture of what is going on with cholesterol in the blood.
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  1. Inflammation is like a fire
  2. LDLs are like fire extinguishers
  3. HDLs are like sweepers that clean up debris

There are a few inflammatory markers in the blood, but the most important factor that is related to heart disease, cholesterol, health, obesity, and our diet is insulin. Insulin is the most anabolic and inflammatory hormone that courses through our blood and it is solely there in response to our diet. When we eat sugar, our pancreas releases insulin to bind to the sugar and take it across the barrier to enter the muscle, or any other tissue.

So, here is the issue. When we eat too much sugar for too long, the insulin doesn't have anywhere to push the sugar to, as the muscles are completely saturated. And we can discuss how a lack of physical exercise will increase the need to muscles to use sugar, but that is for another blog.

So, we have an abundance of sugar, which is inflammatory, or a fire in the blood stream. We have an abundance of insulin, which is inflammatory, another fire, trying to get the sugar out. But neither can do their job because we do not need any more sugar in our tissues. The body has to get this fire out of the blood stream, so it signals the liver to produce a fire extinguisher, LDLs. The LDLs are release from the liver, into the blood and races to every inflammatory particle in the blood. The amount of LDLs is in direct relation to your level of inflammation, or how big of a fire you have created with your diet.

After these LDLs have extinguished the fire that you created by eating too much sugar, here comes the HDLs to the rescue. HDLs are like the sweepers, that collect all of the LDLs that have bound themselves to the inflammation, and transports it back to the liver to be excreted, or thrown away.

Needless to say, your total cholesterol level in your blood, or your HDL + LDL levels are in direct correlation to your body's inflammation level. And more importantly, cholesterol is absolutely VITAL in decreasing your systemic inflammation levels. So blocking your ability to produce a vital hormone to decrease you total cholesterol levels is absolutely absurd.

Stop eating an inflammatory diet, and your liver will not produce as much cholesterol to put out the fire. If you block the ability to make cholesterol with a statin, and you do not decrease your demand for cholesterol by eating better, your health will suffer.... Greatly.

So what happens when you take a Statin drug, that blocks your body's ability to produce cholesterol when your liver is in demand of it. Stay Tuned.

If you are interested in going through this adventure of health with a natural approach, call (812) 799-0668 TODAY and schedule a FREE CONSULTATION, and let's get you back on the path to health and wellness together.

Visit TODAY!

Friday, August 2, 2013

The Gateway Drug. Causing Disease

I hope that you have enjoyed the blog series on The Gateway Drug so far.

I have recently discussed the definition of poison, and how I feel the effects of Antacid use is plausible to being a poisonous substance. I discussed the definition of disease, and I linked the poisonous properties of the Antacid medication to actually causing disease. As you can probably see, I am strongly against the use of any synthetic medication that will alter the normal function of the body, because they only mask the symptoms, and it is inevitable for many symptoms and conditions to be stimulated.

If you notice the first edition to The Gateway Drug Blog Series, I discussed how I feel that a gateway drug was a way for the world of pharmaceutical companies to provide a product that they know, due to the obvious biochemistry, will cause more harm than good.

Now I am going to spend a little time discussing another condition, and how the treacherous side effect of prolonged Antacid use.

Psychological Disorders- What is going wrong? We all know someone that has recently by diagnosed
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Tired of feeling down?
with one of the new hot conditions. Manic Depressive, Bi-Polar, ADHD, ADD, Schizophrenic, etc. All of these conditions  have to do with proper synapses of the neurological system of the brain and nervous system. Some of the common symptoms experienced with psychological disorders include:

  • morbid fears
  • severe fatigue
  • depression
  • paranoia
  • confusion
  • anger
  • suicidal tendencies
As most of you know, Xanax, and many other antidepressant medications are flooding the market because everyone is starting to feel symptoms of depression.

But what if I told you that all of these conditions are simply a B-Vitamin complex deficiency?

It's True!

Look at the symptoms that correspond to a deficiency in B-Vitamins, most important B1, or Thiamine.

Symptoms of Vitamin B Deficiency

  • fears
  • fatigue
  • depression
  • paranoia
  • confusion
  • hostility
  • rage
  • anxiety
I am pretty sure that anyone can see the similarities. 

Here is the fun part... If you have already read my other blogs on The Gateway Drug, you will already know how taking an Antacid Medication can inhibit your ability to digest and assimilate the necessary B-Vitamins from our food.

I guess you understand why it is not a coincidence that every single person that I have seen with a long history of Antacid use has symptoms of depression. The condition is treatable, but you have to stop ingesting the cause.

If you are tired of seeking pain relief with no results, call (812) 799-0668 TODAY and schedule a FREE CONSULTATION, and let's get you back to the PAIN-FREE Life you are missing.

Visit TODAY!